Silent Children's Mission is dedicated to relieving the suffering and neglect of those without a voice. They focus especially on women, children, and their families in extreme poverty. The organization aims to show the poorest of the poor that someone cares about them. They provide basic needs, education, healthcare, spiritual care, and counselling to help people live with dignity.

Silent Children's Mission currently operates in ten developing countries around the world. They collaborate mostly with Catholic bishops, priests, sisters, and lay people in these locations. The organization also serves the poor in Canada, working with various missionaries. Their work spans across multiple continents, focusing on regions where the most vulnerable populations live.

Program highlights include developing trusting relationships with local partners to identify children and families most in need. The organization was founded by Dr. Andrew Simone and his wife Joan, inspired by their work with Mother Teresa. No one receives payment for work within the organization, and no donations are used for fundraising. All work is done voluntarily except for year-end accountant fees. They provide services including advocacy, education, and outreach to various vulnerable groups.